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Quantum Leap Challenge Institutes (QLCI)

U.S. National Science Foundation

Quantum Leap Challenge Institutes are large-scale interdisciplinary research projects motivated by major challenges at the frontiers of quantum information science and technology (QIST). Institutes are expected to catalyze breakthroughs on important problems underpinning QIST, for example in the focus areas of quantum computation, quantum communication, quantum simulation and/or quantum sensing. Successful institutes will coordinate a variety of approaches to specific scientific, technological, and educational goals in these fields, including multiple institutions and building upon multiple disciplines, as motivated by the science and engineering challenges. In so doing, Institutes will nurture a culture of discovery, provide education, training, and workforce development opportunities in the context of cutting-edge research, and demonstrate value-added from synergistic coordination within the institute and with the broader community. Partnerships, infrastructure, industry engagement, outreach, international collaboration, and new applications for QIST should be fostered by Institutes in support of their research, education, and coordination goals. The QLCI program can support awards to continue existing Quantum Leap Challenge Institutes or to establish and operate new Quantum Leap Challenge Institutes. In either case, proposers should follow the same guidance for Challenge Institute proposal preparation described in this solicitation. While this is a crosscutting program, proposals responding to this solicitation must be submitted to the Office of Strategic Initiatives (OSI) in the Directorate of Mathematical and Physical Sciences (MPS). They will subsequently be managed by a cross-disciplinary team of NSF Program Directors. The QLCI program enables NSF multidisciplinary centers for quantum research and education as called for in the National Quantum Initiative (NQI) Act 1 and an NQI Advisory Committee report, Renewing the National Quantum Initiative: Recommendations for Sustaining American Leadership in Quantum Information Science 2 . In alignment with the NQI Act, Quantum Leap Challenge Institutes shall pursue research at the frontiers of quantum information science, engineering, and technology, and explore solutions to important challenges for the development, application, commercialization, and pioneering use of quantum technologies. QLCI Institutes shall also lead education, training, and workforce development activities as may be needed for sustained leadership in QIST and related topics. Coordination both within each Institute and with new partners and the broader ecosystem should also serve to galvanize the community and catalyze the research and education activities in ways that go beyond what smaller projects could accomplish in isolation. 1 National Quantum Initiative Act , Public Law 115-368, of December 21, 2018. 2 https://www.quantum.gov/wp-content/uploads/2023/06/NQIAC-Report-Renewing-the-National-Quantum-Initiative.pdf

eventDeadline: Nov 16 publicUnited States redeemFree

NIJ FY 2026 Evaluation of the Effectiveness of the Bureau of Justice Assistance (BJA) Byrne State Crisis Intervention Program (SCIP)

National Institute of Justice

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Evaluation of the Effectiveness of the Bureau of Justice Assistance (BJA) Byrne State Crisis Intervention Program (SCIP).1 This opportunity will support research and evaluation to assess the effectiveness of programs funded under FYs 2022-2026 BJA’s Byrne SCIP NOFOs. BJA’s Byrne SCIP provides funding for the creation or enhancement of state crisis intervention court proceedings and related programs or initiatives, including extreme risk protection order (ERPO) programs, as well as mental health courts, drug courts, and veterans treatment courts. Such programs or initiatives can include, but are not limited to: 1) Law enforcement crisis interventions; 2) Court-based programming; 3) Referrals to treatment for people in crisis; and 4) ERPO programs. Applicants may apply to assess multiple program areas where applicable. NIJ anticipates making at least one award per topic area for a total of 4 awards. Applicants should clearly state the program area(s) on the title page. This NOFO invites applications proposing a two-phased evaluation strategy to assess Byrne SCIP. The approach includes: • Phase I: Evaluability Assessments. • Phase II: An Evaluation of the Byrne SCIP’s Effectiveness. Applications to this NOFO should include both phases. Applications that do not meet this requirement would not be considered responsive to this funding opportunity.

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Materials Innovation Platforms (MIP)

U.S. National Science Foundation

Materials Innovation Platforms (MIP) is a mid-scale infrastructure program in the Division of Materials Research (DMR) designed to accelerate advances in materials research. MIPs respond to the increasing complexity of materials research that requires close collaboration of interdisciplinary and transdisciplinary teams and access to cutting edge tools. These tools in a user facility benefit both a user program and in-house research, which focus on addressing grand challenges of fundamental science and meet national needs. MIPs embrace the paradigm set forth by the Materials Genome Initiative (MGI), which strives to “discover, manufacture, and deploy advanced materials twice as fast, at a fraction of the cost,” and conduct research through iterative “closed-loop” efforts among the areas of materials synthesis/processing, materials characterization, and theory/modeling/simulation. In addition, they are expected to engage the emerging field of data science in materials research. Each MIP is a scientific ecosystem, which includes in-house research scientists, external users and other scientists who, collectively, form a community of practitioners and share tools, codes, samples, data and know-how. The knowledge sharing is designed to strengthen collaborations among scientists and enable them to work in new ways, fostering new modalities of research and training, for the purpose of accelerating discovery and development of new materials and novel materials phenomena/properties, as well as fostering their eventual deployment. The scientific focus of the MIP program is subject to change from competition to competition. Information about the existing MIPs, from two previous competitions in 2015 and 2019, can be found at mip.org. The third MIP competition, in 2025, will accept proposals on alloys, amorphous, and composite materials. Given that the second MIP competition included an emphasis on biomaterials and polymer research, proposals mainly on these topics will not be considered in the third MIP competition.

eventDeadline: Mar 01 publicUnited States redeemFree

NIAMS P30 Centers Program (P30 - Clinical Trial Not Allowed)

National Institutes of Health

The overall goal of this program is to accelerate scientific discovery, improve research efficiency, and enhance the translation of research findings into improved health outcomes. Centers funded under this program will also foster multidisciplinary collaboration, support workforce development across career stages, and promote training in emerging areas such as data science, artificial intelligence, and implementation research. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) requests applications for the NIAMS P30 Centers Program to support integrated research Centers within its mission areas of skin biology and diseases; bone, muscle, and orthopaedic research; and rheumatic diseases. The NIAMS P30 Centers Program supports Centers that provide coordinated research infrastructure, shared resources, and methodological expertise to advance basic, translational, and clinical research. These Centers are expected to integrate state-of-the-art research resources with capabilities that support clinical and translational research, including the development, testing, and dissemination of novel analytical methods, study designs, outcome measures, and data-driven approaches.

eventDeadline: Nov 23 publicUnited States redeemFree

Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit the development of innovative senescence technologies (SenTecs), or the adaptation of existing technologies focused on identification, characterization and understanding the biological consequences of senescent cell (SnC) heterogeneity in the context of the tissue environments and secretomes to facilitate novel strategies for modulating SnCs in vivo and for predicting the outcomes of targeting SnCs in human aging and in disease conditions. These are five-year, milestone-driven awards consisting of two phases. The first two years constitute the UG3 phase and are focused on SenTec development and demonstration of technology feasibility. The following 3-years is the SenTec application UH3 phase where SenTecs continue to be optimized, refined and validated. In the final year of the UH3 award, SenTecs will undertake a demonstration project conducted in a collaborative effort within SenNet to provide further validation of the proposed SenTec. Applicants are required to submit both UG3 and UH3 projects together when responding to this NOFO. Transition from the UG3 to UH3 phases is not automatic and will occur only after administrative review of each SenTec at the close of Year 2 of the award.

eventDeadline: Dec 14 publicUnited States redeemFree

Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to develop, apply, and test predictive models and perform integrative analyses to determine the impact of genomic variation on genome function. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers also will collaborate with other consortium components to guide and optimize IGVF experimental design, to provide analytical expertise and support for consortium-wide efforts, and to develop and execute shared analysis strategies to meet consortium goals.

biotech

eventDeadline: Dec 14 publicUnited States redeemFree

Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to characterize genomic variation to assess the impact of individual variants on genome function. This will be accomplished by systematically perturbing variants or elements using one or more high-throughput methods; collecting data on the effects of variants in DNA, RNA, or protein-coding elements on molecular, cellular, or organismal phenotypes; and developing robust, reproducible, and portable data processing pipelines. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers are also expected to collaborate with other consortium components to coordinate assays, variants, and cell types, and to develop shared analysis strategies to meet consortium goals.

Research arrow_forward

eventDeadline: Nov 23 publicUnited States redeemFree

Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and disease-relevant cellular senescence signatures (“senotypes”) and associated biomarkers, and will investigate their functional consequences in human health and disease. DVCs are expected to generate and contribute high-quality molecular, cellular, and spatial datasets (including relevant metadata and documentation) and to use complementary experimental systems, as appropriate, to validate senotypes/biomarkers and characterize responses to senescence-associated perturbations or senotherapeutic approaches. DVC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).

eventDeadline: Nov 23 publicUnited States redeemFree

Cellular Senescence Network (SenNet): SenNet Data Coordination and Integration Center (SenNet DCIC) (UM1 Clinical Trials Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to support the SenNet Data Coordination and Integration Center (SenNet DCIC) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). The DCIC will enable timely, high-quality submission, harmonization, integration, and broad dissemination of SenNet-generated data and associated resources by developing and implementing consortium-wide policies, standards, and workflows for data formats, metadata, quality control, and release. The DCIC will maintain and enhance SenNet’s data infrastructure (e.g., portal and associated tools) to support data discovery, access, analysis, visualization, and reuse, and will integrate Stage 1 and Stage 2 outputs to support atlasing and cross-study comparability. DCIC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).